| ncRNA name | hsa-miR-155 |
| ncRNA Category | miRNA |
| Disease name | Pseudomonas aeruginosa keratitis |
| Species | Homo sapiens |
| Tissues/Cell_line | corneas |
| Methods | qPCR, transfection, flow cytometry, Western blot |
| Expression pattern | up-regulated |
| Functional description | miR-155 suppressed the macrophage-mediated bacterial phagocytosis and intracellular killing of P. aeruginosa by targeting Rheb (Ras homolog enriched in brain). miR-155 knockout mice displayed more resistance to P. aeruginosa keratitis. |
| PubMed ID | 24403554 |
| Year | 2014 |
| Title | miR-155 suppresses bacterial clearance in Pseudomonas aeruginosa-induced keratitis by targeting Rheb. |
| Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.