| ncRNA name | hsa-miR-146a |
| ncRNA Category | miRNA |
| Disease name | Graves ophthalmopathy |
| Species | Homo sapiens |
| Tissues/Cell_line | blood, orbital connective tissue |
| Methods | immunofluorescence, qRT-PCR, luciferase reporter assay, transfection, Western blot, MTT assay, flow cytometry, ELISA |
| Expression pattern | up-regulated |
| Functional description | MicroRNA-146a may increase the IL-6 levels and exacerbate GO by directly targeting Notch2.The over-expression of miR-146a markedly facilitated Orbital Fibroblasts (OFs) viability and mitosis whereas markedly suppressed cell apoptosis |
| PubMed ID | 28278511 |
| Year | 2017 |
| Title | Mechanism of MicroRNA-146a/Notch2 Signaling Regulating IL-6 in Graves Ophthalmopathy. |
| Drug-related ncRNA | NO |
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