| ncRNA name | VEGF164 shRNA |
| ncRNA Category | shRNA |
| Disease name | retinopathy of prematurity (ROP) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | retinas |
| Methods | shRNA injection, retinal imaging, ERG, OCT, immunohistochemistry |
| Expression pattern | associated |
| Functional description | Lectin-stained retinal flat mounts analyzed for areas of avascular/total retina (AVA) and intravitreal neovascular/total retina (IVNV) showed initial significantly reduced IVNV by L-VEGFAshRNA and L-VEGF164shRNA compared to control, luciferase-shRNA lentivirus, without late recurrence. |
| PubMed ID | 29386650 |
| Year | 2018 |
| Title | Targeted Knockdown of Overexpressed VEGFA or VEGF164 in Müller cells maintains retinal function by triggering different signaling mechanisms. |
| Drug-related ncRNA | NA |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.