| ncRNA name | rno-miR-21 |
| ncRNA Category | miRNA |
| Disease name | optic nerve injury |
| Species | Rattus norvegicus |
| Tissues/Cell_line | optic nerves |
| Methods | transfection, immunohistochemistry, Western blot, qRT-PCR, in situ hybridization |
| Expression pattern | up-regulated |
| Functional description | Inhibition of miR-21 regulates the EGFR pathway, ameliorating excessive astrocyte activation and glial scar progression and promoting axonal regeneration and alleviating impairment in F-VEP function in a model of ONC. |
| PubMed ID | 29709341 |
| Year | 2018 |
| Title | Inhibition of miR-21 ameliorates excessive astrocyte activation and promotes axon regeneration following optic nerve crush. |
| Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.