| ncRNA name | MMP-9 shRNA |
| ncRNA Category | shRNA |
| Disease name | herpes simplex virus keratitis |
| Species | Mus musculus |
| Tissues/Cell_line | corneas |
| Methods | shRNA knockdown, RT-PCR, qPCR, gelatin zymography, immunohistochemistry |
| Expression pattern | associated |
| Functional description | Delivery of the pshMMP-9 stopped angiogenesis and decreased the severity of herpetic keratitis. However, interferon-alpha (IFN-alpha) and IFN- beta induced by pshRNA might also contribute to inhibition of herpetic simplex keratitis (HSK) in the cornea. |
| PubMed ID | 15989422 |
| Year | 2005 |
| Title | Blocking mouse MMP-9 production in tumor cells and mouse cornea by short hairpin (sh) RNA encoding plasmids. |
| Drug-related ncRNA | NA |
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