| ncRNA name | TLR4 siRNA |
| ncRNA Category | siRNA |
| Disease name | fungal keratitis |
| Species | Homo sapiens |
| Tissues/Cell_line | telomerase-immortalized human corneal epithelial cells (THCEs) |
| Methods | siRNA transfection, RT-PCR, Western blot, ELISA |
| Expression pattern | associated |
| Functional description | Treatment with TLR2- or TLR4-siRNA plasmid reduced TLR2 or TLR4 expression level in THCE when compared with controls, and caused a significant decrease in A. fumigatus-induced IL-1beta and IL-6 production. |
| PubMed ID | 19341426 |
| Year | 2009 |
| Title | Innate responses of corneal epithelial cells against Aspergillus fumigatus challenge. |
| Drug-related ncRNA | NO |
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