| ncRNA name | LSD1 siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Bos taurus |
| Tissues/Cell_line | bovine retinal endothelial cells (BRECs) |
| Methods | Chromatin immunoprecipitation (CHIP), qPCR, Western blot, Nrf2-DNA binding activity |
| Expression pattern | associated |
| Functional description | LSD1 siRNA abrogated the glucose-induced decrease in H3K4me1 at Gclc-ARE4 and ameliorated decreases in Nrf2 binding at Gclc-ARE4 and Gclc transcripts. |
| PubMed ID | 25016074 |
| Year | 2014 |
| Title | Epigenetic modifications of Nrf2-mediated glutamate-cysteine ligase: implications for the development of diabetic retinopathy and the metabolic memory phenomenon associated with its continued progression. |
| Drug-related ncRNA | NO |
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