| ncRNA name | Cx43 siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | rat retinal endothelial cells (RRECs) |
| Methods | siRNA transfection, Western blot, Co-immunoprecipitation, immunostaining |
| Expression pattern | associated |
| Functional description | Cells transfected with Cx43 siRNA and grown in N medium showed significant downregulation in occludin and ZO-1 expression, and exhibited increased cell monolayer permeability. |
| PubMed ID | 24008412 |
| Year | 2013 |
| Title | Effects of high glucose-induced Cx43 downregulation on occludin and ZO-1 expression and tight junction barrier function in retinal endothelial cells. |
| Drug-related ncRNA | NO |
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