| ncRNA name | LSD1 siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Bos taurus |
| Tissues/Cell_line | bovine retinal endothelial cells (BRECs) |
| Methods | siRNA transfection, semi-qPCR, qRT-PCR, Western blot, ELISA |
| Expression pattern | associated |
| Functional description | LSD1 siRNA ameliorated the glucose-induced decrease in H3K9me2 and increase in p65 at the MMP-9 promoter, and prevented MMP-9 activation, mitochondrial damage, and cell apoptosis. |
| PubMed ID | 23423566 |
| Year | 2013 |
| Title | Regulation of matrix metalloproteinase-9 by epigenetic modifications and the development of diabetic retinopathy. |
| Drug-related ncRNA | NO |
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