| ncRNA name | hsa-miR-150 |
| ncRNA Category | miRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Homo sapiens |
| Tissues/Cell_line | human umbilical vein endothelial cells (HUVECs) |
| Methods | Western blot, qPCR |
| Expression pattern | down-regulated |
| Functional description | Deletion of miR-150 significantly increased the retinal pathological angiogenesis in HFD induced type 2 diabetic mice. Overexpression of miR-150 in cultured endothelial cells caused a significant reduction of vascular endothelial growth factor receptor 2 (VEGFR2) protein levels. |
| PubMed ID | 27304911 |
| Year | 2016 |
| Title | Deletion of miR-150 Exacerbates Retinal Vascular Overgrowth in High-Fat-Diet Induced Diabetic Mice. |
| Drug-related ncRNA | NO |
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