| ncRNA name | CTGF siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | retinas; Rat-2 fibroblasts |
| Methods | siRNA transfection and injection, immunohistochemistry, qRT-PCR, Western blot |
| Expression pattern | associated |
| Functional description | Treatment of diabetic rats with CTGF siRNA decreased laminin β1, collagen IVα3 mRNA, and CTGF mRNA and protein but did not affect fibronectin or vascular endothelial growth factor mRNA levels. |
| PubMed ID | 22511849 |
| Year | 2012 |
| Title | Inhibition of connective tissue growth factor by small interfering ribonucleic acid prevents increase in extracellular matrix molecules in a rodent model of diabetic retinopathy. |
| Drug-related ncRNA | NO |
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