| ncRNA name | hsa-miR-146b-3p |
| ncRNA Category | miRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Homo sapiens |
| Tissues/Cell_line | human monocyte cell line U937; vitreous |
| Methods | immunofluorescence, transfection, luciferase reporter assay, qRT-PCR, ELISA |
| Expression pattern | down-regulated |
| Functional description | In the vitreous of diabetic patients, decreased miR-146b-3p is associated with increased ADA2 activity. Ectopic expression of miR-146b-3p suppressed ADA2 expression, activity, and TNF-α release in the AGA-treated human macrophages. |
| PubMed ID | 25815338 |
| Year | 2015 |
| Title | MicroRNA-146b-3p regulates retinal inflammation by suppressing adenosine deaminase-2 in diabetes. |
| Drug-related ncRNA | NO |
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