| ncRNA name | hsa-miR-146 |
| ncRNA Category | miRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Homo sapiens |
| Tissues/Cell_line | human retinal endothelial cells (HRECs); human embryonic kidney cell line HEK293 |
| Methods | transfection, qRT-PCR, luciferase reporter assay, Western blot |
| Expression pattern | up-regulated |
| Functional description | We identified that caspase-recruitment domain (CARD)-containing protein 10 (CARD10), an essential scaffold/adaptor protein of GPCR-mediated NF-κB activation pathway, is a direct target of miR-146. |
| PubMed ID | 24985472 |
| Year | 2014 |
| Title | MicroRNA-146 inhibits thrombin-induced NF-κB activation and subsequent inflammatory responses in human retinal endothelial cells. |
| Drug-related ncRNA | NO |
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