| ncRNA name | Egr-1 siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Homo sapiens |
| Tissues/Cell_line | human retinal endothelial cells (hRECs) |
| Methods | siRNA transfection, qPCR, immunofluorescence, Western blot |
| Expression pattern | associated |
| Functional description | Egr-1 downstream gene targets, tissue factor (TF) and intercellular adhesion molecule-1 (ICAM-1) expression were increased in hRECs which was reduced by Egr-1 silencing in hyperglycemia. |
| PubMed ID | 29307595 |
| Year | 2018 |
| Title | Hyperglycemia induced early growth response-1 regulates vascular dysfunction in human retinal endothelial cells. |
| Drug-related ncRNA | NO |
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