| ncRNA name | CYLD siRNA |
| ncRNA Category | siRNA |
| Disease name | choroidal neovascularization (CNV) |
| Species | Mus musculus |
| Tissues/Cell_line | human RPE cell line ARPE-19; human umbilical vein endothelial cells (HUVECs) |
| Methods | FFA, H&E staining, immunofluorescence, siRNA transfection, Western blot, immunoprecipitation, ELISA, qPCR |
| Expression pattern | associated |
| Functional description | Silencing CYLD by siRNA remarkably blocked OX-LDL-induced VEGF secretion compared with the control. Tube formation experiment also proved that silencing CYLD mRNA decreased the tube length of HUVECs after OX-LDL stimulation. |
| PubMed ID | 29081889 |
| Year | 2017 |
| Title | Salvianolic Acid A Inhibits OX-LDL Effects on Exacerbating Choroidal Neovascularization via Downregulating CYLD. |
| Drug-related ncRNA | NO |
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