| ncRNA name | hsa-miR-125b |
| ncRNA Category | miRNA |
| Disease name | cataract |
| Species | Homo sapiens |
| Tissues/Cell_line | anterior lens capsule; human lens epithelial cell line: SRA01/04 |
| Methods | qRT-PCR, TUNEL assay, flow cytometry, Western blot, luciferase reporter assay |
| Expression pattern | down-regulated |
| Functional description | miR-125b was downregulated in both age-related cataract tissue and lens epithelial cell apoptosis induced by UV irradiation. In vitro, miR-125b regulates human lens epithelial cell apoptosis at least in part by directly targeting p53. |
| PubMed ID | 25312242 |
| Year | 2014 |
| Title | MicroRNA-125b inhibits lens epithelial cell apoptosis by targeting p53 in age-related cataract. |
| Drug-related ncRNA | NO |
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