| ncRNA name | PF-04523655 |
| ncRNA Category | siRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Homo sapiens |
| Tissues/Cell_line | retinas |
| Methods | siRNA injection, OCT, FFA |
| Expression pattern | associated |
| Functional description | In this early, underpowered study evaluating treatments for neovascular AMD, the combination of PF with ranibizumab led to an average gain in BCVA that was more than with ranibizumab monotherapy. |
| PubMed ID | 22683252 |
| Year | 2012 |
| Title | Evaluation of the siRNA PF-04523655 versus ranibizumab for the treatment of neovascular age-related macular degeneration (MONET Study). |
| Drug-related ncRNA | NO |
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