| ncRNA name | hsa-miR-589-5p |
| ncRNA Category | miRNA |
| Disease name | age-related cataract |
| Species | Homo sapiens |
| Tissues/Cell_line | human lens epithelial cell line SRA01/04 |
| Methods | transfection, qRT-PCR, luciferase reporter assay |
| Expression pattern | associated |
| Functional description | The C allele of XPC-2229090 increase the risk with ARNC. The mechanism underlying might be due to the stronger interation of the C allele with hsa-miR-589-5p, resulting in lower XPC expression and DNA repair capability than the individuals carring G allele in lens. |
| PubMed ID | 30315181 |
| Year | 2018 |
| Title | MicroRNA binding mediated Functional sequence variant in 3'-UTR of DNA repair Gene XPC in Age-related Cataract. |
| Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.