| ncRNA name | hsa-miR-211 |
| ncRNA Category | miRNA |
| Disease name | age-related cataract |
| Species | Homo sapiens |
| Tissues/Cell_line | anterior lens capsules; human epithelial cell line SRA01/04 |
| Methods | qRT-PCR, transfection, MTS assay, Western blot, luciferase reporter assay |
| Expression pattern | up-regulated |
| Functional description | miR-211 is highly expressed in the anterior lens capsules of patients with age-related cataracts. By negatively regulating the expression of SIRT1, miR-211 promotes lens epithelial cell apoptosis and inhibits lens epithelial cell proliferation. |
| PubMed ID | 29487807 |
| Year | 2018 |
| Title | miR-211 promotes lens epithelial cells apoptosis by targeting silent mating-type information regulation 2 homolog 1 in age-related cataracts. |
| Drug-related ncRNA | NO |
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