| ncRNA name | H19 |
| ncRNA Category | lncRNA |
| ID | 283120 |
| Ensembl | ENSG00000130600 |
| Synonyms | ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, PRO2605, WT2 |
| Disease name | age-related cataract |
| Species | Homo sapiens |
| Tissues/Cell_line | human lens epithelium samples |
| Methods | lncRNA sequencing, qRT-PCR, transfection, MTT assay, Calcein-AM and proPIdium iodide double staining, Rhodamine 123 and Hoechst double staining, EdU incorporation assay, transwell assay, luciferase reporter assay, Western blot |
| Expression pattern | up-regulated |
| Functional description | We identified 63 differentially expressed lncRNAs, including 37 down-regulated lncRNAs and 26 upregulated lncRNAs (nuclear cataractous versus transparent). H19 regulates HLECs function through miR-675-mediated CRYAA expression. |
| PubMed ID | 30286462 |
| Year | 2018 |
| Title | Long Non-Coding RNA H19 Regulates Human Lens Epithelial Cells Function. |
| Drug-related ncRNA | NO |
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