A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-219-5p
ncRNA name hsa-miR-219-5p
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human RPE cells
Methods RT-PCR, MTT assay, flow cytometry, dual‑luciferase reporter assay, Western blot
Expression pattern up-regulated
Functional description miR-219-5p was involved in the progression of DR through regulating human RPE cell apoptosis by modulation of the LRH-1/Wnt/β-Catenin signaling pathway.
PubMed ID 29749515
Year 2018
Title Significant role of microRNA‑219‑5p in diabetic retinopathy and its mechanism of action.
Drug-related ncRNA NO

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