A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-218-5p
ncRNA name hsa-miR-218-5p
ncRNA Category miRNA
Disease name pterygium
Species Homo sapiens
Tissues/Cell_line pterygium tissues and normal bulbar conjunctival tissues
Methods transfection, qRT-PCR, Western blot, luciferase reporter assay, scratch wound healing assay
Expression pattern down-regulated
Functional description miR-218-5p downregulated the expression of EGFR via PI3K/Akt/mTOR pathway in pterygium tissues and hPECs and inhibited hPECs migration and proliferation.
PubMed ID 30243568
Year 2019
Title MicroRNA-218-5p inhibit the migration and proliferation of pterygium epithelial cells by targeting EGFR via PI3K/Akt/mTOR signaling pathway.
Drug-related ncRNA NO

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