ncRNA name | hsa-miR-218-5p |
ncRNA Category | miRNA |
Disease name | pterygium |
Species | Homo sapiens |
Tissues/Cell_line | pterygium tissues and normal bulbar conjunctival tissues |
Methods | transfection, qRT-PCR, Western blot, luciferase reporter assay, scratch wound healing assay |
Expression pattern | down-regulated |
Functional description | miR-218-5p downregulated the expression of EGFR via PI3K/Akt/mTOR pathway in pterygium tissues and hPECs and inhibited hPECs migration and proliferation. |
PubMed ID | 30243568 |
Year | 2019 |
Title | MicroRNA-218-5p inhibit the migration and proliferation of pterygium epithelial cells by targeting EGFR via PI3K/Akt/mTOR signaling pathway. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.