|uveal melanoma (UM)
|liver perfusate, blood; human malignant melanoma cell line A375; human malignant melanoma cell line MML-1; human breast cancer cell line HTB-133; human lung carcinoma cell line HTB-177; human mast cell line HMC-1.2
|flow cytometry, Western blot, qPCR
|Cluster 1 consisted of four miRNAs (miR-216a, miR217, miR129-5p and miR-203) that were expressed almost equally in patients and the lung, breast and melanoma cell lines, but not in the human mast cell line HMC-1. KEGG pathway analysis showed that metabolism and signalling pathways, including “glycosaminoglycan biosynthesis” and “TGF-beta signalling”, were among the most common pathways.
|MicroRNA in exosomes isolated directly from the liver circulation in patients with metastatic uveal melanoma.
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