|pterygium tissues, normal conjunctival tissues
|microarray, qRT-PCR, fluorescent in situ hybridization (FISH), immunofluorescent staining, flow cytometry, luciferase reporter assay
|miR-215 could play a role in inhibiting fibroblast proliferation in ocular surface conjunctiva. Dampening of this miR-215 could result in increased fibroblast cell cycling and proliferation, with possibly increased fibroblastic production of matrix, inducing pterygium formation.
|MicroRNA-215 Regulates Fibroblast Function: Insights from a Human Fibrotic Disease.
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