| ncRNA name | hsa-miR-214 |
| ncRNA Category | miRNA |
| Disease name | cataract |
| Species | Homo sapiens |
| Tissues/Cell_line | lens anterior capsular samples; human lens epithelial cell line SRA01/04 |
| Methods | qRT-PCR, Western blot, immunofluorescence staining, TUNEL assay, luciferase reporter assay |
| Expression pattern | down-regulated |
| Functional description | We demonstrated for the first time that caspase-1 is a functional downstream target of miR-214 and knockdown of KCNQ1OT1 significantly increased the expression of miR-214. |
| PubMed ID | 28535504 |
| Year | 2017 |
| Title | Long Non-Coding RNA KCNQ1OT1 Promotes Cataractogenesis via miR-214 and Activation of the Caspase-1 Pathway. |
| Drug-related ncRNA | NO |
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