| ncRNA name | hsa-miR-211 |
| ncRNA Category | miRNA |
| Disease name | glaucoma |
| Species | Homo sapiens |
| Tissues/Cell_line | aqueous humor |
| Methods | cell viability assay, apoptosis assay, qRT-PCR, immunoblot, fluorescent in situ hybridization (FISH), immunofluorescence, luciferase reporter assay |
| Expression pattern | up-regulated |
| Functional description | Our findings show that miR-211 negatively modulates cell survival programs upon high pressure challenge by regulating Frs2 signaling, and they define roles for miR-211/Frs2 cascade in a regulatory feedback loop that mediates the pathogenesis of glaucoma. |
| PubMed ID | 30131252 |
| Year | 2018 |
| Title | Intraocular miR-211 exacerbates pressure-induced cell death in retinal ganglion cells via direct repression of FRS2 signaling. |
| Drug-related ncRNA | NO |
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