ncRNA name | hsa-miR-211 |
ncRNA Category | miRNA |
Disease name | age-related cataract |
Species | Homo sapiens |
Tissues/Cell_line | anterior lens capsules; human epithelial cell line SRA01/04 |
Methods | qRT-PCR, transfection, MTS assay, Western blot |
Expression pattern | up-regulated |
Functional description | miR-211 is upregulated in the anterior lens capsules of age-related cataract patients. miR-211 decreased the antioxidative stress capacity of lens epithelial cells by upregulating p53 and Bax, while inhibiting cell proliferation and repair. |
PubMed ID | 29600165 |
Year | 2018 |
Title | miR-211 regulates the antioxidant function of lens epithelial cells affected by age-related cataracts. |
Drug-related ncRNA | NO |
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