A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-211
ncRNA name hsa-miR-211
ncRNA Category miRNA
Disease name age-related cataract
Species Homo sapiens
Tissues/Cell_line anterior lens capsules; human epithelial cell line SRA01/04
Methods qRT-PCR, transfection, MTS assay, Western blot
Expression pattern up-regulated
Functional description miR-211 is upregulated in the anterior lens capsules of age-related cataract patients. miR-211 decreased the antioxidative stress capacity of lens epithelial cells by upregulating p53 and Bax, while inhibiting cell proliferation and repair.
PubMed ID 29600165
Year 2018
Title miR-211 regulates the antioxidant function of lens epithelial cells affected by age-related cataracts.
Drug-related ncRNA NO

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