ncRNA name | hsa-miR-211 |
ncRNA Category | miRNA |
Disease name | proliferative vitreoretinopathy (PVR) |
Species | Homo sapiens |
Tissues/Cell_line | human fetal RPE cells, human fetal choroidal fibroblast cells |
Methods | microarray, qRT-PCR, transfection, Western blot, immunofluorescence |
Expression pattern | down-regulated |
Functional description | miR-204/211 promote RPE differentiation, suggesting that miR-204/211-based therapeutics may be effective treatments for diseases that involve RPE dedifferentiation such as proliferative vitreoretinopathy. |
PubMed ID | 22523078 |
Year | 2012 |
Title | Microphthalmia-associated transcription factor (MITF) promotes differentiation of human retinal pigment epithelium (RPE) by regulating microRNAs-204/211 expression. |
Drug-related ncRNA | NO |
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