A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-21-5p
ncRNA name hsa-miR-21-5p
ncRNA Category miRNA
Disease name retinal neovascularization
Species Homo sapiens
Tissues/Cell_line human retinal microvascular endothelial cells (HRMVECs)
Methods RNA-seq
Expression pattern down-regulated
Functional description Analysis of the most abundant miRNAs in the HRMVEC miRNome (representing at least 1% of the miRNome) was conducted and identified miR-21-5p, miR-29a-3p, miR-100-5p and miR-126-5p/-3p to be differently expressed by at least 15% between resting conditions and angiogenic conditions.
PubMed ID 30615884
Year 2019
Title Impact of angiogenic activation and inhibition on miRNA profiles of human retinal endothelial cells.
Drug-related ncRNA NO

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