|thyroid tissues, blood
|next-generation sequencing, qRT-PCR
|miRNA-21-5p was associated with a higher risk of developing GD and a worse clinical outcome, and it was correlated to persistent disease in the long-term follow-up, with a better predictive value than the currently used TRAb levels.miR-21-5p can regulate the Th1/Th2 balance and promote Th17 differentiation by inhibiting Smad-7.
|A MicroRNA Signature for Evaluation of Risk and Severity of Autoimmune Thyroid Diseases.
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