A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-21-5p
ncRNA name hsa-miR-21-5p
ncRNA Category miRNA
Disease name Graves disease
Species Homo sapiens
Tissues/Cell_line thyroid tissues, blood
Methods next-generation sequencing, qRT-PCR
Expression pattern up-regulated
Functional description miRNA-21-5p was associated with a higher risk of developing GD and a worse clinical outcome, and it was correlated to persistent disease in the long-term follow-up, with a better predictive value than the currently used TRAb levels.miR-21-5p can regulate the Th1/Th2 balance and promote Th17 differentiation by inhibiting Smad-7.
PubMed ID 29325052
Year 2018
Title A MicroRNA Signature for Evaluation of Risk and Severity of Autoimmune Thyroid Diseases.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.