| ncRNA name | hsa-miR-21-3p |
| ncRNA Category | miRNA |
| Disease name | age-related cataract |
| Species | Homo sapiens |
| Tissues/Cell_line | capsule samples; human embryonic kidney cell line HEK293T; human hepatoblastoma cell line HepG2 |
| Methods | Comet assay, qPCR, luciferase reporter assay |
| Expression pattern | associated |
| Functional description | The association of SNP rs2278414 with ARC might involve an altered miRNA regulation of ZNF350. The in vitro experiment indicated that miR-21-3p and miR-150-5p specifically downregulated luciferase reporter expression in the cell lines transfected with rs2278414 A allele compared with rs2278414 G. |
| PubMed ID | 27586871 |
| Year | 2016 |
| Title | Functional SNP in 3'-UTR MicroRNA-Binding Site of ZNF350 Confers Risk for Age-Related Cataract. |
| Drug-related ncRNA | NO |
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