ncRNA name | hsa-miR-21 |
ncRNA Category | miRNA |
Disease name | proliferative vitreoretinopathy (PVR) |
Species | Homo sapiens |
Tissues/Cell_line | vitreous humor; human RPE cell line ARPE-19 |
Methods | microarray, qRT-PCR, transfection, Enhanced Green Fluorescent Protein (EGFP) reporter, immunocytochemical analysis |
Expression pattern | up-regulated |
Functional description | Our studies have identified miR-21 as a potential disease-modifying miRNA in the vitreous humor that is involved in the development of retinal fibrosis and may be a novel marker of PVD. |
PubMed ID | 27351379 |
Year | 2016 |
Title | Upregulation of Mir-21 Levels in the Vitreous Humor Is Associated with Development of Proliferative Vitreoretinal Disease. |
Drug-related ncRNA | NO |
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