|proliferative vitreoretinopathy (PVR)
|vitreous humor; human RPE cell line ARPE-19
|microarray, qRT-PCR, transfection, Enhanced Green Fluorescent Protein (EGFP) reporter, immunocytochemical analysis
|Our studies have identified miR-21 as a potential disease-modifying miRNA in the vitreous humor that is involved in the development of retinal fibrosis and may be a novel marker of PVD.
|Upregulation of Mir-21 Levels in the Vitreous Humor Is Associated with Development of Proliferative Vitreoretinal Disease.
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