ncRNA name | hsa-miR-21 |
ncRNA Category | miRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | vitreous humor, UM tumor samples, choroidal melanocytes |
Methods | microarray, RT-PCR |
Expression pattern | up-regulated |
Functional description | miR-21 is upregulated in VH, exosomes from VH of UM patients. Upregulation of miR-21 and miR-146a was detected in formalin-fixed, paraffin-embedded UM, suggesting that VH or serum alterations in UM could be the consequence of disregulation arising from tumoral cells. |
PubMed ID | 25951497 |
Year | 2015 |
Title | miRNA profiling in vitreous humor, vitreal exosomes and serum from uveal melanoma patients: Pathological and diagnostic implications. |
Drug-related ncRNA | NO |
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