A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-21
ncRNA name hsa-miR-21
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line vitreous humor, UM tumor samples, choroidal melanocytes
Methods microarray, RT-PCR
Expression pattern up-regulated
Functional description miR-21 is upregulated in VH, exosomes from VH of UM patients. Upregulation of miR-21 and miR-146a was detected in formalin-fixed, paraffin-embedded UM, suggesting that VH or serum alterations in UM could be the consequence of disregulation arising from tumoral cells.
PubMed ID 25951497
Year 2015
Title miRNA profiling in vitreous humor, vitreal exosomes and serum from uveal melanoma patients: Pathological and diagnostic implications.
Drug-related ncRNA NO

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