A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-21
ncRNA name hsa-miR-21
ncRNA Category miRNA
Disease name Graves ophthalmopathy
Species Homo sapiens
Tissues/Cell_line orbital tissues
Methods qPCR, Western blot, transfection, flow cytometry
Expression pattern up-regulated
Functional description The present study shows that miR-21 regulates cell proliferation, apoptosis, and differentiation in orbital fibroblasts from TAO, and acts as a mediator in TGF-β1-induced collagen production.
PubMed ID 25873777
Year 2015
Title MiRNA-21 promotes fibrosis in orbital fibroblasts from thyroid-associated ophthalmopathy.
Drug-related ncRNA NO

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