A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-21
ncRNA name hsa-miR-21
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell lines Y79, WERI-RB1 and RB355
Methods microarray, qRT-PCR, transfection, Western blot
Expression pattern up-regulated
Functional description These data suggest that miR-21 down-regulates Rb1 by targeting PDCD4 tumor suppressor.
PubMed ID 25520758
Year 2014
Title MicroRNA-21 Down-regulates Rb1 Expression by Targeting PDCD4 in Retinoblastoma.
Drug-related ncRNA NO

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