ncRNA name | hsa-miR-21 |
ncRNA Category | miRNA |
Disease name | Behcet's disease (BD) |
Species | Homo sapiens |
Tissues/Cell_line | peripheral blood mononuclear cells (PBMCs) |
Methods | RT-PCR, qPCR, flow cytometry, ELISA |
Expression pattern | up-regulated |
Functional description | miR-21 was correlated with HSV-induced BD-like inflammation in mice and BD patients. The expression of miR-21 was regulated by antagomir in mice. Treatment with colchicine or pentoxifylline down-regulated the level of miR-21 with improved symptoms in mice. |
PubMed ID | 25849652 |
Year | 2015 |
Title | The relevance of miRNA-21 in HSV-induced inflammation in a mouse model. |
Drug-related ncRNA | YES (colchicine, pentoxifylline) |
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