|Behcet's disease (BD)
|peripheral blood mononuclear cells (PBMCs)
|RT-PCR, qPCR, flow cytometry, ELISA
|miR-21 was correlated with HSV-induced BD-like inflammation in mice and BD patients. The expression of miR-21 was regulated by antagomir in mice. Treatment with colchicine or pentoxifylline down-regulated the level of miR-21 with improved symptoms in mice.
|The relevance of miRNA-21 in HSV-induced inflammation in a mouse model.
|YES (colchicine, pentoxifylline)
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