A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-182
ncRNA name hsa-miR-182
ncRNA Category miRNA
Disease name primary open-angle glaucoma (POAG)
Species Homo sapiens
Tissues/Cell_line ciliary bodies, corneas, retinas and trabecular meshwork
Methods RNA-seq, ddPCR
Expression pattern up-regulated
Functional description Only rs76481776 in MIR182 gene was associated with POAG after adjustment for multiple comparisons. The risk allele T has been associated with elevated miR-182 expression in vitro. Data from ddPCR and miRNA-Seq confirmed miR-182 expression in all examined ocular tissues and TM-derived exosomes.
PubMed ID 27537254
Year 2016
Title A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium.
Drug-related ncRNA NO

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