A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-155
ncRNA name hsa-miR-155
ncRNA Category miRNA
Disease name Pseudomonas aeruginosa keratitis
Species Homo sapiens
Tissues/Cell_line corneas
Methods qPCR, transfection, flow cytometry, Western blot
Expression pattern up-regulated
Functional description miR-155 suppressed the macrophage-mediated bacterial phagocytosis and intracellular killing of P. aeruginosa by targeting Rheb (Ras homolog enriched in brain). miR-155 knockout mice displayed more resistance to P. aeruginosa keratitis.
PubMed ID 24403554
Year 2014
Title miR-155 suppresses bacterial clearance in Pseudomonas aeruginosa-induced keratitis by targeting Rheb.
Drug-related ncRNA NO

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