A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-146a-5p
ncRNA name hsa-miR-146a-5p
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human retinal endothelial cells (HRECs), human RPE cell line ARPE-19
Methods MTS assay, transfection, qRT-PCR, Western blot
Expression pattern differentially expressed
Functional description miR-145/-146a expression decreased gradually in high-glucose-treated HRECs, but increased in hyperglycemia-exposed RPE cells and in diabetic rats.
PubMed ID 28706953
Year 2017
Title Differentially Expressed MicroRNAs in the Development of Early Diabetic Retinopathy.
Drug-related ncRNA NO

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