ncRNA name | hsa-miR-146a-5p |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human retinal endothelial cells (HRECs), human RPE cell line ARPE-19 |
Methods | MTS assay, transfection, qRT-PCR, Western blot |
Expression pattern | differentially expressed |
Functional description | miR-145/-146a expression decreased gradually in high-glucose-treated HRECs, but increased in hyperglycemia-exposed RPE cells and in diabetic rats. |
PubMed ID | 28706953 |
Year | 2017 |
Title | Differentially Expressed MicroRNAs in the Development of Early Diabetic Retinopathy. |
Drug-related ncRNA | NO |
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