ncRNA name | hsa-miR-146a-5p |
ncRNA Category | miRNA |
Disease name | conjunctival melanoma |
Species | Homo sapiens |
Tissues/Cell_line | conjunctival malignant melanoma samples, normal conjunctivas |
Methods | microarray |
Expression pattern | up-regulated |
Functional description | MicroRNA expression analysis revealed 25 tumour-specific microRNAs in conjunctival melanoma. Five possibly oncogenic miRNAs (miR-20b-5p, miR-146b-5p, miR-146a-5p, miR-506-3p and miR-509-3p) were up-regulated. Seven microRNAs (miR-30d-5p, miR-138-5p, miR-146a-5p, miR-500a-5p, miR-501-3p, miR-501-5p and miR-502-3p) were significantly and simultaneously up-regulated in both stage T1 and stage T2 tumours, and were associated with increased tumour thickness. |
PubMed ID | 27192168 |
Year | 2016 |
Title | Conjunctival malignant melanoma in Denmark: epidemiology, treatment and prognosis with special emphasis on tumorigenesis and genetic profile. |
Drug-related ncRNA | NO |
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