ncRNA name | hsa-miR-146a-5p |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human retinal microvascular endothelial cells |
Methods | transfection, qPCR, Western blot, ELISA |
Expression pattern | down-regulated |
Functional description | The results suggest that miR-146a is a potential therapeutic target for reducing inflammation in REC through inhibition of TLR4/NF-κB and TNFα. |
PubMed ID | 26997759 |
Year | 2016 |
Title | miR-146a Attenuates Inflammatory Pathways Mediated by TLR4/NF-κB and TNFα to Protect Primary Human Retinal Microvascular Endothelial Cells Grown in High Glucose. |
Drug-related ncRNA | NO |
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