ncRNA name | hsa-miR-146a |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human retinal endothelial cells (HRECs) |
Methods | transfection, qPCR, Western blot, ELISA |
Expression pattern | down-regulated |
Functional description | miR-146a suppressed IL-6 signaling, leading to reduced levels of STAT3 and VEGF in REC in high glucose conditions, leading to decreased apoptosis. |
PubMed ID | 28433754 |
Year | 2017 |
Title | miR-146a suppresses STAT3/VEGF pathways and reduces apoptosis through IL-6 signaling in primary human retinal microvascular endothelial cells in high glucose conditions. |
Drug-related ncRNA | NO |
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