A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-146a
ncRNA name hsa-miR-146a
ncRNA Category miRNA
Disease name Graves ophthalmopathy
Species Homo sapiens
Tissues/Cell_line orbital adipose/connective tissue
Methods microarray, qRT-PCR, ELISA, Western blot
Expression pattern up-regulated
Functional description MicroRNA 146a was upregulated by inflammatory stress in orbital fibroblasts. Our results indicated that miR-146a had a positive effect on the anti-inflammatory process. MicroRNA 146a may play a role in the regulation of inflammation in orbital fibroblasts, and may participate in the pathogenesis of GO.
PubMed ID 27494344
Year 2016
Title Role of miR-146a in the Regulation of Inflammation in an In Vitro Model of Graves' Orbitopathy.
Drug-related ncRNA NO

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