A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-146a
ncRNA name hsa-miR-146a
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line vitreous humor, serum, UM tumor samples, choroidal melanocytes
Methods microarray, RT-PCR
Expression pattern up-regulated
Functional description miR-146a is upregulated in VH, exosomes from VH, serum and exosomes from serum of UM patients. Real Time PCR analysis showed that miR-21, miR-34a and miR-146a were statistically upregulated in UM cells. Upregulation of miR-146a in serum of UM patients could derive from melanocytes through exosome secretion.
PubMed ID 25951497
Year 2015
Title miRNA profiling in vitreous humor, vitreal exosomes and serum from uveal melanoma patients: Pathological and diagnostic implications.
Drug-related ncRNA NO

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