ncRNA name | hsa-miR-146a |
ncRNA Category | miRNA |
Disease name | Graves disease |
Species | Homo sapiens |
Tissues/Cell_line | peripheral blood mononuclear cells (PBMCs) |
Methods | flow cytometry, microarray, qPCR, Western blot |
Expression pattern | down-regulated |
Functional description | There were 23 up-regulated and 14 down-regulated miRNAs between three GD sample pools and control sample pools. miR-519e–5p, miR-30a–5p, miR-19b, miR-146a and miR-155 were validated by LNA qPCR in another 30 patients with iuGD and 30 controls. |
PubMed ID | 25233152 |
Year | 2014 |
Title | Integrative analysis of mRNA and miRNA array data reveals the suppression of retinoic acid pathway in regulatory T cells of Graves' disease. |
Drug-related ncRNA | NO |
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