A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-146a
ncRNA name hsa-miR-146a
ncRNA Category miRNA
Disease name Graves ophthalmopathy
Species Homo sapiens
Tissues/Cell_line serum
Methods qRT-PCR
Expression pattern down-regulated
Functional description Active-GO and inactive-GO group had significantly lower miR-146a expressions than control. Active-GO group had significantly lower miR-146a than inactive-GO group. Serum levels of IL-17 and miR-146a were both significantly correlated with clinical activity score (CAS) in GO patients. There was a significant negative correlation of circulating miR-146a expression with serum IL-17 levels (P < 0.01).
PubMed ID 25100151
Year 2014
Title Circulating levels of miR-146a and IL-17 are significantly correlated with the clinical activity of Graves' ophthalmopathy.
Drug-related ncRNA NO

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