A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-146a
ncRNA name hsa-miR-146a
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human retinal endothelial cells (HRECs); human Müller cells (HMCs); human RPE cell line ARPE-19
Methods transfection, qPCR, Western blot
Expression pattern down-regulated
Functional description Diabetes-induced dysregulation of daily rhythms of miR-146a and inflammatory pathways under miR-146a control have potential implications for the development of diabetic retinopathy.
PubMed ID 24867582
Year 2014
Title Regulation of retinal inflammation by rhythmic expression of MiR-146a in diabetic retina.
Drug-related ncRNA NO

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