ncRNA name | hsa-miR-146a |
ncRNA Category | miRNA |
Disease name | diabetic keratopathy |
Species | Homo sapiens |
Tissues/Cell_line | corneas; human corneal epithelial cells (HCECs) |
Methods | microarray, qRT-PCR, in situ hybridization, transfection, Western blot, immunocytochemistry |
Expression pattern | up-regulated |
Functional description | HCEC transfection with h-miR-146a or h-miR-424 significantly retarded wound closure. Cells treated with h-miR-146a or h-miR-424 had decreased p-p38 and p-EGFR staining. Functional roles: Inflammatory responses, hematopoiesis, migration and proliferation. |
PubMed ID | 24376808 |
Year | 2013 |
Title | Differentially expressed wound healing-related microRNAs in the human diabetic cornea. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.