ncRNA name | hsa-miR-125b |
ncRNA Category | miRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | liver perfusate, blood; human malignant melanoma cell line A375; human malignant melanoma cell line MML-1; human breast cancer cell line HTB-133; human lung carcinoma cell line HTB-177; human mast cell line HMC-1.2 |
Methods | flow cytometry, Western blot, qPCR |
Expression pattern | detectable |
Functional description | Cluster 2 consisted of seven miRNAs (miR-9*, miR125a-5p, miR-25, miR-125b, miR-335, miR-19a and miR-9) that were also expressed almost equally in patients and the five tested cell lines. KEGG pathway analysis showed that biosynthesis and metabolism pathways, such as “glycosaminoglycan biosynthesis”, “mucin type-O-glycan biosynthesis” and “biotin metabolism”, were among the most common pathways. |
PubMed ID | 25510783 |
Year | 2014 |
Title | MicroRNA in exosomes isolated directly from the liver circulation in patients with metastatic uveal melanoma. |
Drug-related ncRNA | NO |
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