|uveal melanoma (UM)
|liver perfusate, blood; human malignant melanoma cell line A375; human malignant melanoma cell line MML-1; human breast cancer cell line HTB-133; human lung carcinoma cell line HTB-177; human mast cell line HMC-1.2
|flow cytometry, Western blot, qPCR
|Cluster 2 consisted of seven miRNAs (miR-9*, miR125a-5p, miR-25, miR-125b, miR-335, miR-19a and miR-9) that were also expressed almost equally in patients and the five tested cell lines. KEGG pathway analysis showed that biosynthesis and metabolism pathways, such as “glycosaminoglycan biosynthesis”, “mucin type-O-glycan biosynthesis” and “biotin metabolism”, were among the most common pathways.
|MicroRNA in exosomes isolated directly from the liver circulation in patients with metastatic uveal melanoma.
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