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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of hsa-miR-125b
ncRNA name hsa-miR-125b
ncRNA Category miRNA
Disease name ocular adnexal lymphoma
Species Homo sapiens
Tissues/Cell_line ocular adnexal region specimens
Methods microarray
Expression pattern down-regulated
Functional description Differential miRNA expression analysis identified 43 significantly differentially expressed miRNAs in oDLBCL (diffuse large B-cell lymphoma) versus oEMZL (extranodal marginal zone lymphoma), 2 upregulated, and 41 downregulated in oDLBCL relative to oEMZL. miR-125b has been reported previously to be under negative transcriptional regulation by NFKB1.
PubMed ID 23821202
Year 2013
Title MicroRNA profiling in ocular adnexal lymphoma: a role for MYC and NFKB1 mediated dysregulation of microRNA expression in aggressive disease.
Drug-related ncRNA NO

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